Results for: Science and Medicine
FREUD, SIGMUND (1856-1939). Austrian neurologist, writer and founder of psychoanalysis.
Extraordinary Typed Letter Signed, in German, 2 pages on one folio sheet of his printed, "Prof. Dr. Freud" stationery, Bergasse 19, Vienna, November, 10, 1924.
Price: $14,500.00
more info
add to cart
Extraordinary Typed Letter Signed, in German, 2 pages on one folio sheet of his printed, "Prof. Dr. Freud" stationery, Bergasse 19, Vienna, November, 10, 1924.
Price: $14,500.00
more info
add to cart
JENNER, EDWARD (1749-1823). English scientist who pioneered the development of vaccination by developing smallpox vaccine.
Autograph Manuscript Signed, 8vo, n.p., ca. 1822.
Price: $12,000.00
more info
add to cart
Autograph Manuscript Signed, 8vo, n.p., ca. 1822.
Price: $12,000.00
more info
add to cart
EINSTEIN, ALBERT (1879-1955) German-born theoretical physicist who is best known for his theory of relativity and specifically mass-energy equivalence, E = mc2. He was awarded the 1921 Nobel Prize in Physics "for his services to Theoretical Physics, and especially for his discovery of the law of the photoelectric effect.
Autograph Letter Signed, in German, 2 pages on one 4to sheet, June 5, 1929.
Price: $11,000.00
more info
add to cart
Autograph Letter Signed, in German, 2 pages on one 4to sheet, June 5, 1929.
Price: $11,000.00
more info
add to cart
BOYLE, ROBERT (1627-1691). Important Irish-born English scientist who was a natural philosopher, chemist, physicist, inventor, and gentleman scientist, also noted for his writings in theology. He is best known for the formulation of Boyle's law. Although his research and personal philosophy clearly has its roots in the alchemical tradition.
Autograph Letter Signed. two pages 4to, Oxford, November 11, 1665.
Price: $8,500.00
more info
add to cart
Autograph Letter Signed. two pages 4to, Oxford, November 11, 1665.
Price: $8,500.00
more info
add to cart
EINSTEIN, ALBERT (1879 1955). Einstein was a German born physicist, humanitarian, Nobel Prize winner and the founder of the General Theory of Relativity.
Typed Letter Signed, in English, 4to, Princeton. March 28, 1938.
Price: $6,500.00
more info
add to cart
Typed Letter Signed, in English, 4to, Princeton. March 28, 1938.
Price: $6,500.00
more info
add to cart
OLSON, CHARLES (1910-1970).
Rare Typed Letter Signed, 2 full separate 4to pages, Lerma, Campeche, Mexico, April 13, 1951.
Price: $4,000.00
more info
add to cart
Rare Typed Letter Signed, 2 full separate 4to pages, Lerma, Campeche, Mexico, April 13, 1951.
Price: $4,000.00
more info
add to cart
BOHR, NIELS (1885-1962) Danish physicist who made fundamental contributions to understanding atomic structure and quantum mechanics, for which he received the Nobel Prize in Physics in 1922. He was also part of the team of physicists working on the Manhattan Project.
Typed Letter Signed, in Danish, 4to, Copenhagen, February 15, 1955. Also included is the rare 21 page carbon copy of the transcript to Bohrs lecture, in English, Science and the Unity of Knowledge given October 28, 1954, at the conferenc
Price: $3,750.00
more info
add to cart
Typed Letter Signed, in Danish, 4to, Copenhagen, February 15, 1955. Also included is the rare 21 page carbon copy of the transcript to Bohrs lecture, in English, Science and the Unity of Knowledge given October 28, 1954, at the conferenc
Price: $3,750.00
more info
add to cart
HOFFMANN, FRIEDRICH. (1669-1742) German physician; experimented with various remedies. He was an influential theorist who systematized medicine.
Manuscript Letter Signed, in Latin, 4 pages, Halle, March 15, 1694.
Price: $3,650.00
more info
add to cart
Manuscript Letter Signed, in Latin, 4 pages, Halle, March 15, 1694.
Price: $3,650.00
more info
add to cart
ROENTGEN, WILHELM (1845-1923) German physicist, discoverer of X-rays, and winner of the first ever Nobel Prize in Physics (1901).
A.L.S., in German, 1 p, watermarked 8vo, Weilheim, Germany, Dec. 24, 1916.
Price: $3,500.00
more info
add to cart
A.L.S., in German, 1 p, watermarked 8vo, Weilheim, Germany, Dec. 24, 1916.
Price: $3,500.00
more info
add to cart
CALDANI , LEOPOLDDO MARCO ANTONIO (1725 - 1813) Italian anatomist and physiologist. He is noted for his experimental studies on the function of the spinal cord and for the introduction of electricity in the physiology of the nerves. His most celebrated work is his anatomical atlas made in collaboration with his nephew.
Excellent Autograph Letter Signed, in Italian, 4to, Padua, April 12, 1789.
Price: $3,450.00
more info
add to cart
Excellent Autograph Letter Signed, in Italian, 4to, Padua, April 12, 1789.
Price: $3,450.00
more info
add to cart
SABIN, ALBERT (1906-93) Russian born, American medical researcher who is best known for having developed the widely successful oral vaccine for polio.
Autograph Manuscript Signed, in pencil, titled, Science and the Future Direction of Humanity, 12 lined 4to pages, George Washington University, February 12, 1986.
Price: $3,250.00
more info
add to cart
Autograph Manuscript Signed, in pencil, titled, Science and the Future Direction of Humanity, 12 lined 4to pages, George Washington University, February 12, 1986.
Price: $3,250.00
more info
add to cart
MERCURI, SCIPIONE GIROLAMO (1540-1615) Roman medical physician, scientist, and author of what can be considered the first Italian treatise on obstetrics from the sixteenth century. The book, La comare o raccoglitrice (1596) which contains the first indications for the execution of cesarean sections.
Beautiful Autograph Letter Signed, in Italian, oblong 8vo, n.d.
Price: $3,000.00
more info
add to cart
Beautiful Autograph Letter Signed, in Italian, oblong 8vo, n.d.
Price: $3,000.00
more info
add to cart
SOMMERFELD,.ARNOLD (1868-1951). German theoretical physicist who pioneered developments in atomic and quantum physics, and also educated and groomed a large number of students for the new era of theoretical physics. He introduced the fine-structure constant into quantum mechanics.
Autograph Document Signed, in German, 4to, Munich, September 28, 1950.
Price: $2,850.00
more info
add to cart
Autograph Document Signed, in German, 4to, Munich, September 28, 1950.
Price: $2,850.00
more info
add to cart
CALDANI , LEOPOLDO MARCO ANTONIO 17251813) Italian anatomist and physiologist. He is noted for his experimental studies on the function of the spinal cord and for the introduction of electricity in the physiology of the nerves. His most celebrated work is his anatomical atlas made in collaboration with his nephew.
Autograph Letter Signed, in Italian, two 4to pages, Padua, March 9, 1794.
Price: $2,750.00
more info
add to cart
Autograph Letter Signed, in Italian, two 4to pages, Padua, March 9, 1794.
Price: $2,750.00
more info
add to cart
EDISON, THOMAS ALVA (1847-1931) American inventor. Among his many inventions, of which he patented over a thousand, were an automatic telegraph repeater, printing telegraph, electric pen, the photograph and the incandescent lamp.
Rare Early Autograph Letter Signed, oblong 8vo, New York, February 9, 1883.
Price: $2,350.00
more info
add to cart
Rare Early Autograph Letter Signed, oblong 8vo, New York, February 9, 1883.
Price: $2,350.00
more info
add to cart
BOHR, NIELS (1885-1962). Danish physicist who received the Nobel Prize for Physics in1922. He is the main contributor to the understanding of the structure of the atom as well as to the development of quantum mechanics.
Rare Autograph Quotation Signed, in English, small oblong 8vo, Paris, December 20, 1951.
Price: $2,350.00
more info
add to cart
Rare Autograph Quotation Signed, in English, small oblong 8vo, Paris, December 20, 1951.
Price: $2,350.00
more info
add to cart
AMPERE, ANDRE-MARIE (1775-1836). French physicist and mathematician who is generally credited as one of the main discoverers of electromagnetism. The SI unit of measurement of electric current, the ampere, is named after him.
Magnificent Manuscript and Printed Document Signed, oblong folio, with attractive borders and red wax seal, Paris, during its session of April 30, 1808.
Price: $2,350.00
more info
add to cart
Magnificent Manuscript and Printed Document Signed, oblong folio, with attractive borders and red wax seal, Paris, during its session of April 30, 1808.
Price: $2,350.00
more info
add to cart
SABIN, ALBERT (1906-93). American physician and medical researcher. Created effective vaccines while working with the Army Medical Corps during World War II. +
A.M.S., thirteen numbered 4to pages with one additional page of additions, n.p., 1980.
Price: $2,200.00
more info
add to cart
A.M.S., thirteen numbered 4to pages with one additional page of additions, n.p., 1980.
Price: $2,200.00
more info
add to cart
SABIN, ALBERT (1906-93) American physician and medical researcher. Created effective vaccines while working with the Army Medical Corps during World War II. Released his attenuated-virus polio vaccine for use by other researchers. Created an oral v
Typed Letter Signed on "Public Health Service National Institutes of Health" stationery 4to, Bethesda, MD, June 6, 1986, and Autograph Manuscript Signed, 15 pages 4to, for a lecture in Washington, DC on April 15, 1986.
Price: $2,200.00
more info
add to cart
Typed Letter Signed on "Public Health Service National Institutes of Health" stationery 4to, Bethesda, MD, June 6, 1986, and Autograph Manuscript Signed, 15 pages 4to, for a lecture in Washington, DC on April 15, 1986.
Price: $2,200.00
more info
add to cart
LOUIS, DR. P.C. ANTOINE (1723-92) French medical doctor. Shortly before his death, with Joseph Ignace Guillotin (1738-1814), he began construction of the executing machine that now bears the name of his co-inventor.
Autograph Letter Signed, in French, two pages with integral address page, 4to, Paris, June 10, 1764.
Price: $1,950.00
more info
add to cart
Autograph Letter Signed, in French, two pages with integral address page, 4to, Paris, June 10, 1764.
Price: $1,950.00
more info
add to cart

![To his son. “My dear Tetel, Even if I write you so little, I love you very dearly and often think how hard you must be cramming for your graduation. But that too will be over and you will be a free little man, as free as circumstances will allow, which will be a serious limitation in itself. I wonder when I will get to see you? The beautiful sailboat will be finished by the end of the week. But for now it will have to stay on Plesch’s estate, and I along with it. You will be able to relax and recover. I am doing quite well, much better than a few months ago. But I am not quite over it. The house is being built in Caputh now (nomen est omen) [Latin: “a fitting name”]. It is terribly expensive, and the city has made it so ugly that I refused their gift. I intend to move to Caputh fulltime, because the dual living arrangements would get too expensive. You will be charmed by the location. It should be finished by the end of September. Mama’s letter about the money from New York has not arrived yet; do remind her of it and give her my love. Write me a little note sometime soon (no need for more in your current stress) and let me send you a kiss.” Signed, “Your Papa!” He continues in a postscript. “I enjoyed my visit with Ada, and I have the impression that the two are living quite happily. The situation has turned out much less dire than I had feared a while back.” To his son. “My dear Tetel, Even if I write you so little, I love you very dearly and often think how hard you must be cramming for your graduation. But that too will be over and you will be a free little man, as free as circumstances will allow, which will be a serious limitation in itself. I wonder when I will get to see you? The beautiful sailboat will be finished by the end of the week. But for now it will have to stay on Plesch’s estate, and I along with it. You will be able to relax and recover. I am doing quite well, much better than a few months ago. But I am not quite over it. The house is being built in Caputh now (nomen est omen) [Latin: “a fitting name”]. It is terribly expensive, and the city has made it so ugly that I refused their gift. I intend to move to Caputh fulltime, because the dual living arrangements would get too expensive. You will be charmed by the location. It should be finished by the end of September. Mama’s letter about the money from New York has not arrived yet; do remind her of it and give her my love. Write me a little note sometime soon (no need for more in your current stress) and let me send you a kiss.” Signed, “Your Papa!” He continues in a postscript. “I enjoyed my visit with Ada, and I have the impression that the two are living quite happily. The situation has turned out much less dire than I had feared a while back.”](/schulson/images/items/80x160/1903.jpg)
![To. C.O.S. [Carl Ortwin Sauer] A professor at University of California, Berkeley for 50 years where he influenced a generation of geographers, trying to unify the areas of physical and human geography through a historical methodology. "Do you know anyone or anything (Texas oil foundation, or, old-line outfit with merely loot of mercantilism) which would take young workers in your rear to a small piece of some loot (500 or 1000 bucks) . I am going to be absolutely out of funds, done in, with all the last of the Guggenheim gone and what personal monies wife and I added to get us here, to keep us, and to manage digging, study, and moves, up to now . -what looks like my business- is, the art of the language of Mayan glyphs. And if I don't get some help quick, I am going to have to creep back to the States without having got the base work done on such important grounds as Uaxactun-Tikal, and Copan-Quirigus. As well as that basket of all but the 60 ton pieces, the Musco Nacionel, in the City, over there. I write to you, because of course, you are, to me the jefe or culture morphology there is in this early today's .I am scared to death of you, and, this week, when the first number of the new Boston magazine is out, with a long prose piece of mine, chiefly on the Sumerians, in which I quote you, occupying its center, constituting its "cultural" position, I am so scared I don't dare send you a copy.).I have dug, on my own: small sites, chiefly, along this west coast, from Jaina, on the north, to Champoton; just to get my hand in. I have also ranged the northern Yucatan sites: Uhiohen, Uxmal, Kabah, Labna-Sayil, Santa Rose Xtampak, Edzna. And I have bore in hard, on collections, basing this work on the fine small Campeche Museum. What I have found is, I take it, the simplest of discrepancies: the Maya thing was, if it was anything, a triumph of culture, yet, in the modern uncovering of its remains, and their examination, the conspicuously absent thing has been a methodology of culture-morphology and of men able to use same methodology. It is general, so far as I can make out, to the whole research as well as the digging and judgments in the field." Olson then continues by discussing digging, it is to continue to study and to examine the complex of Mayan "writing"- stone and wood inscriptions, the codices, and living Mayan speech as well as the host of other things (custom, legend, myths, etc.) which bear on language- until I am in a position to write what I tentatively can call a study of The Art Of The Language Of Mayan Glyphs." He continues with very specific lengthy details about Mayan glyphs, topics that certainly were a great influence on his own writing. This letter is signed, "Charles Olson" To. C.O.S. [Carl Ortwin Sauer] A professor at University of California, Berkeley for 50 years where he influenced a generation of geographers, trying to unify the areas of physical and human geography through a historical methodology. "Do you know anyone or anything (Texas oil foundation, or, old-line outfit with merely loot of mercantilism) which would take young workers in your rear to a small piece of some loot (500 or 1000 bucks) . I am going to be absolutely out of funds, done in, with all the last of the Guggenheim gone and what personal monies wife and I added to get us here, to keep us, and to manage digging, study, and moves, up to now . -what looks like my business- is, the art of the language of Mayan glyphs. And if I don't get some help quick, I am going to have to creep back to the States without having got the base work done on such important grounds as Uaxactun-Tikal, and Copan-Quirigus. As well as that basket of all but the 60 ton pieces, the Musco Nacionel, in the City, over there. I write to you, because of course, you are, to me the jefe or culture morphology there is in this early today's .I am scared to death of you, and, this week, when the first number of the new Boston magazine is out, with a long prose piece of mine, chiefly on the Sumerians, in which I quote you, occupying its center, constituting its "cultural" position, I am so scared I don't dare send you a copy.).I have dug, on my own: small sites, chiefly, along this west coast, from Jaina, on the north, to Champoton; just to get my hand in. I have also ranged the northern Yucatan sites: Uhiohen, Uxmal, Kabah, Labna-Sayil, Santa Rose Xtampak, Edzna. And I have bore in hard, on collections, basing this work on the fine small Campeche Museum. What I have found is, I take it, the simplest of discrepancies: the Maya thing was, if it was anything, a triumph of culture, yet, in the modern uncovering of its remains, and their examination, the conspicuously absent thing has been a methodology of culture-morphology and of men able to use same methodology. It is general, so far as I can make out, to the whole research as well as the digging and judgments in the field." Olson then continues by discussing digging, it is to continue to study and to examine the complex of Mayan "writing"- stone and wood inscriptions, the codices, and living Mayan speech as well as the host of other things (custom, legend, myths, etc.) which bear on language- until I am in a position to write what I tentatively can call a study of The Art Of The Language Of Mayan Glyphs." He continues with very specific lengthy details about Mayan glyphs, topics that certainly were a great influence on his own writing. This letter is signed, "Charles Olson"](/schulson/images/items/80x160/209.jpg)



![He writes a lengthy letter: "Idiocy that, if in the story used here it is literally not equivocal, is only a few months old and was produced for no obvious reason, should be surmountable in some way by [medical] skill. I say should be because if the young man has never given any sign of mental weakness whatsoever in his childhood, you have to worry that the illness is congenital and that it developed little by little to the current condition and that perhaps it increases even more when, with the beginning of puberty and of the preparation of prolific in the designated organs, no beneficial change occurs. In similar cases [medical] skill has no more effective treatments than those of elimination and bloodletting; and those are administered by surgery or medication. Surgery suggest first of all the opening of the hemorrhoidal veins by way of leeches. Submerged in a cold bath or shower with constant dripping on the crown of the head. And finally cauterizing in the nape of the neck. If it turns out that those treatments have to be used over a long time, a skilled person should perform them. As far as pharmaceutical remedies are concerned, it is probably difficult to make the young patient swallow medication. You may be able to trick him pretending to be making coffee while preparing oriental senna, or with another method. Or finally, by having a solution of hellebor prepared to be taken a few times in the discussed quantity, with which the common can be swallowed. If the practice of these remedies shows improvement from June to autumn, the writer suggests bone grafting. This result would probably have to be a long time and be maintained until healing, with the warning not to reverse it with reactions." He writes a lengthy letter: "Idiocy that, if in the story used here it is literally not equivocal, is only a few months old and was produced for no obvious reason, should be surmountable in some way by [medical] skill. I say should be because if the young man has never given any sign of mental weakness whatsoever in his childhood, you have to worry that the illness is congenital and that it developed little by little to the current condition and that perhaps it increases even more when, with the beginning of puberty and of the preparation of prolific in the designated organs, no beneficial change occurs. In similar cases [medical] skill has no more effective treatments than those of elimination and bloodletting; and those are administered by surgery or medication. Surgery suggest first of all the opening of the hemorrhoidal veins by way of leeches. Submerged in a cold bath or shower with constant dripping on the crown of the head. And finally cauterizing in the nape of the neck. If it turns out that those treatments have to be used over a long time, a skilled person should perform them. As far as pharmaceutical remedies are concerned, it is probably difficult to make the young patient swallow medication. You may be able to trick him pretending to be making coffee while preparing oriental senna, or with another method. Or finally, by having a solution of hellebor prepared to be taken a few times in the discussed quantity, with which the common can be swallowed. If the practice of these remedies shows improvement from June to autumn, the writer suggests bone grafting. This result would probably have to be a long time and be maintained until healing, with the warning not to reverse it with reactions."](/schulson/images/items/80x160/676.jpg)
![Mercuri writes, “The person delivering the letter is a friend of mine and an exiled patriot of the Church State and of Padua, which [used to pay] for his service, but I am asking you to assume the burden for 8 - 10 days….” Handwritten address on the back. “To Gio. Battista Pico Secr.y of the S.A.” of Parma. Mercuri writes, “The person delivering the letter is a friend of mine and an exiled patriot of the Church State and of Padua, which [used to pay] for his service, but I am asking you to assume the burden for 8 - 10 days….” Handwritten address on the back. “To Gio. Battista Pico Secr.y of the S.A.” of Parma.](/schulson/images/items/80x160/1781.jpg)

![To his Son-in-Law, ”There couldn’t be more reassuring news than what you gave me. Oh, what beautiful horns have grown on your enemies! They are so long that they stretch from Padua to Tavia. I can only hope that a similar extension will grow all the way from their buttocks to their throat and suffocate them just as they deserve. The recent news from here is that the magistrate has not agreed on the desired stipend that was not considerable…. So while I have taken on your cause, I am writing a forceful letter to a powerful patrician my son-in-law to move the disposition of His Excellency Gabrieli, the actual state inquirer, so that he then will speak forcefully to E. Bembo who wants to do everything to please His Exc. Gabrieli. Please remind His E. Vindmorin of the public letter so that you can collect (just like others, and, as was done with others, it did not happen barbarically to me) the usual anticipated sum, namely 24 ducats. A letter like that needs to be issued to you with the aid of the Senate. I imagine you have given yourself pleasant recourse at the house that is more or less yours, that is with my most beloved daughter. I hope and pray that such news did not overwhelm her sensibility too forcefully. More immediately, even though it has happened to you, no professor has ever been elected, and this is good. I gave the two ducats back to the noted Domenican friar as a gift. If you ever find yourself short, know that you must not think about the [table / food]. There is a spot here in my philosopher’s refectory, that is, there is enough here to sustain life. As far as sleeping goes, there is room in the house of my servant just a few steps across from me. My bed is really large, but I don’t want to sleep with you. Having been far from your house for several weeks, I don’t want to compensate and be too close now. Adieu, dear friend, let’s show the rascals for what they are; one of these days they are bound to come to a bad end.” Signed, “Adieu again, Your Caldani” In a postscript, Caldani continues, “If you have opportunity to see the generous and estimable Sig. Sanferno, greet him in my name and remind him of my affairs so that we may be given what has been withheld from me and given to other people.” To his Son-in-Law, ”There couldn’t be more reassuring news than what you gave me. Oh, what beautiful horns have grown on your enemies! They are so long that they stretch from Padua to Tavia. I can only hope that a similar extension will grow all the way from their buttocks to their throat and suffocate them just as they deserve. The recent news from here is that the magistrate has not agreed on the desired stipend that was not considerable…. So while I have taken on your cause, I am writing a forceful letter to a powerful patrician my son-in-law to move the disposition of His Excellency Gabrieli, the actual state inquirer, so that he then will speak forcefully to E. Bembo who wants to do everything to please His Exc. Gabrieli. Please remind His E. Vindmorin of the public letter so that you can collect (just like others, and, as was done with others, it did not happen barbarically to me) the usual anticipated sum, namely 24 ducats. A letter like that needs to be issued to you with the aid of the Senate. I imagine you have given yourself pleasant recourse at the house that is more or less yours, that is with my most beloved daughter. I hope and pray that such news did not overwhelm her sensibility too forcefully. More immediately, even though it has happened to you, no professor has ever been elected, and this is good. I gave the two ducats back to the noted Domenican friar as a gift. If you ever find yourself short, know that you must not think about the [table / food]. There is a spot here in my philosopher’s refectory, that is, there is enough here to sustain life. As far as sleeping goes, there is room in the house of my servant just a few steps across from me. My bed is really large, but I don’t want to sleep with you. Having been far from your house for several weeks, I don’t want to compensate and be too close now. Adieu, dear friend, let’s show the rascals for what they are; one of these days they are bound to come to a bad end.” Signed, “Adieu again, Your Caldani” In a postscript, Caldani continues, “If you have opportunity to see the generous and estimable Sig. Sanferno, greet him in my name and remind him of my affairs so that we may be given what has been withheld from me and given to other people.”](/schulson/images/items/80x160/1510.jpg)

![Dr. Sabin, now 80 years old, is sending a manuscript as a gift. ". Because of your moving 'bitte, bitte' appeal I tried very hard to find some pages of original manuscript that I am sending you herewith." He signs the letter "Albert B. Sabin," in his capacity as Senior Expert Consultant of the Fogarty International Center. The 1986 lecture is interesting, one he prepared for the Twenty-third Cosmos Club Award Lecture at the Cosmos Club in Washington, DC. He titles it "Role of My Cooperation with Soviet Scientists in the Conquest of Polio: Some Lessons and Challenges". "So you will not be thinking of polio in the abstract - as an ancient crippling and occasionally fatal disease - let me quickly show a few slides of children with the miserable residues of this disease. Some people think that this crippling disease which has been part of the human heritage since earliest evolutionary times has already been conquered, i.e. eliminated, brought under control, or even eradicated." It is mostly true for the cooler countries having less than half the world's population, where "during the last 20 years the oral polio vaccine has prevented about five million cases of persistent paralysis and perhaps 500,000 deaths. But it is not true for most tropical and sub-tropical, economically underdeveloped countries inhabited by about 2,500 million people . where crippling polio remains a serious public health problem with an estimated average of 250,000 -400,000 new paralytic cases per year" and uncounted deaths, particularly in Asia and Africa. Persistent paralytic polio is caused primarily by any of three viruses; it is these three that Sabin's vaccines prevent. The Sabin oral vaccines use live virus, which lives in the patient's gut as a benign infection and stimulates production of antibodies which also kill the three terrible versions of polio. Once vaccinated a person excretes live virus and actually passes the benign infection to others, a kind of passive vaccination. Reported polio infection in the U.S. has dropped from 13,500 per 100 million before 1955 to 4 per 100 million in 1985. But there are additional viruses which cause polio and for which there is no vaccine, says Sabin. "Even people who should know better seem to forget that in the prevaccine era - a little over 30 years ago - it was estimated that perhaps as much as 1% of all . cases in the USA was caused by other viruses . against which it is impractical to prepare vaccines." They accounted for nearly 32,500 polio cases per year in the U.S. alone, and statistically 325 of those should still result in persistent paralysis. "And yet during the last 11 years, excluding a few imported cases, the yearly average of [reported cases] has been about 7. What has happened to all the paralytic polio cases caused by other viruses that we used to have in this country 25 to 35 years ago?" The implication is that the industrial world's medical guard may be down and polio may be going undiagnosed in places like the U.S. and Europe. Since he has always known that polio is still rampant in Third World countries, he knows that the danger is still there. Written in pencil, with holograph corrections in pencil and pen. He has written "Albert B. Sabin" on the title page of the lecture. Dr. Sabin, now 80 years old, is sending a manuscript as a gift. ". Because of your moving 'bitte, bitte' appeal I tried very hard to find some pages of original manuscript that I am sending you herewith." He signs the letter "Albert B. Sabin," in his capacity as Senior Expert Consultant of the Fogarty International Center. The 1986 lecture is interesting, one he prepared for the Twenty-third Cosmos Club Award Lecture at the Cosmos Club in Washington, DC. He titles it "Role of My Cooperation with Soviet Scientists in the Conquest of Polio: Some Lessons and Challenges". "So you will not be thinking of polio in the abstract - as an ancient crippling and occasionally fatal disease - let me quickly show a few slides of children with the miserable residues of this disease. Some people think that this crippling disease which has been part of the human heritage since earliest evolutionary times has already been conquered, i.e. eliminated, brought under control, or even eradicated." It is mostly true for the cooler countries having less than half the world's population, where "during the last 20 years the oral polio vaccine has prevented about five million cases of persistent paralysis and perhaps 500,000 deaths. But it is not true for most tropical and sub-tropical, economically underdeveloped countries inhabited by about 2,500 million people . where crippling polio remains a serious public health problem with an estimated average of 250,000 -400,000 new paralytic cases per year" and uncounted deaths, particularly in Asia and Africa. Persistent paralytic polio is caused primarily by any of three viruses; it is these three that Sabin's vaccines prevent. The Sabin oral vaccines use live virus, which lives in the patient's gut as a benign infection and stimulates production of antibodies which also kill the three terrible versions of polio. Once vaccinated a person excretes live virus and actually passes the benign infection to others, a kind of passive vaccination. Reported polio infection in the U.S. has dropped from 13,500 per 100 million before 1955 to 4 per 100 million in 1985. But there are additional viruses which cause polio and for which there is no vaccine, says Sabin. "Even people who should know better seem to forget that in the prevaccine era - a little over 30 years ago - it was estimated that perhaps as much as 1% of all . cases in the USA was caused by other viruses . against which it is impractical to prepare vaccines." They accounted for nearly 32,500 polio cases per year in the U.S. alone, and statistically 325 of those should still result in persistent paralysis. "And yet during the last 11 years, excluding a few imported cases, the yearly average of [reported cases] has been about 7. What has happened to all the paralytic polio cases caused by other viruses that we used to have in this country 25 to 35 years ago?" The implication is that the industrial world's medical guard may be down and polio may be going undiagnosed in places like the U.S. and Europe. Since he has always known that polio is still rampant in Third World countries, he knows that the danger is still there. Written in pencil, with holograph corrections in pencil and pen. He has written "Albert B. Sabin" on the title page of the lecture.](/schulson/images/items/80x160/435.jpg)

