Our letter presents Dr. Jenner working as a physician in general practice in the English countryside of Gloucestershire. Here, he advises a home remedy for child whose sickness he doubts. "...your little boy is undoubtedly somewhat indispose'd but it appears to me that he is at present more under the influence of artificial than natural sickness...." He tells the mother that he will visit that day, but "in the mean time put aside your antimony and give him for his dinner some good apple dumplings with cream & sugar, or anything of the like kind...." He signs," E. Jenner."
The letter appears to have been cut from its integral address leaf with rough edges and remains of a border at the bottom. Slight split along margin fold not affecting text.